Piperazine → 8-Methylamino-4-(1-oxido-thiomorpholino)-2-piperazino-pyrimido-[5,4-d]-pyrimidine

HRID 1139755Notes

Reaction equation

HRID 1139755 reaction equation
[CH2:21]1[CH2:22][NH:23][CH2:24][CH2:25][NH:26]1.[Cl:1][c:2]1[n:3][c:4]([N:14]2[CH2:15][CH2:16][S:17](=[O:20])[CH2:18][CH2:19]2)[c:5]2[c:6]([n:7]1)[c:8]([NH:12][CH3:13])[n:9][cH:10][n:11]2.[O:27]1[CH2:28][CH2:29][O:30][CH2:31][CH2:32]1>>[c:2]1([N:23]2[CH2:22][CH2:21][NH:26][CH2:25][CH2:24]2)[n:3][c:4]([N:14]2[CH2:15][CH2:16][S:17](=[O:20])[CH2:18][CH2:19]2)[c:5]2[c:6]([n:7]1)[c:8]([NH:12][CH3:13])[n:9][cH:10][n:11]2

Participants

4

Reactant 3

HCID 4837PiperazineHCID 312751,4-DioxaneHCID 128169982-Chloro-8-methylamino-4-(1-oxido-thiomorpholino)-pyrimido-[5,4-d]-pyrimidine

Product 1

HCID 128170548-Methylamino-4-(1-oxido-thiomorpholino)-2-piperazino-pyrimido-[5,4-d]-pyrimidine

Sources & evidence

ORD record
ord-2aff1a3238244dd2abb3965389041d2e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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