Acetonitrile → 2-[4-[[3-hydroxy-1-[6-(trifluoromethyl)pyridin-3-yl]propyl]amino]-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-6-yl]-5-methylbenzonitrile
Reaction equation
[CH3:45][C:46]#[N:47].[CH:36]([N:37]([CH2:38][CH3:39])[CH:40]([CH3:41])[CH3:42])([CH3:43])[CH3:44].[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][n:7]1)[CH2:8][CH2:9][N:10]([c:12]1[c:13]([C:14]#[N:15])[cH:16][c:17]([CH3:20])[cH:18][cH:19]1)[CH2:11]2.[NH2:21][CH:22]([CH2:23][CH2:24][OH:25])[c:26]1[cH:27][n:28][c:29]([C:32]([F:33])([F:34])[F:35])[cH:30][cH:31]1>>[c:2]1([NH:21][CH:22]([CH2:23][CH2:24][OH:25])[c:26]2[cH:27][n:28][c:29]([C:32]([F:33])([F:34])[F:35])[cH:30][cH:31]2)[c:3]2[c:4]([n:5][cH:6][n:7]1)[CH2:8][CH2:9][N:10]([c:12]1[c:13]([C:14]#[N:15])[cH:16][c:17]([CH3:20])[cH:18][cH:19]1)[CH2:11]2Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-edad40da9ec446b68d3d4d17daa52887
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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