Triethylamine → 4-chloro-N-[5-chloro-2-(2,3-dihydro-pyrido[3,2-b][1,4]oxazine-4-carbonyl)-pyridin-3-yl]-3-trifluoromethyl-benzenesulfonamide

HRID 114021Notes

Reaction equation

HRID 114021 reaction equation
[CH3:36][CH2:37][N:38]([CH2:39][CH3:40])[CH2:41][CH3:42].[Cl:1][c:2]1[cH:3][c:4]([NH:11][S:12](=[O:13])(=[O:14])[c:15]2[cH:16][c:17]([C:22]([F:23])([F:24])[F:25])[c:18]([Cl:21])[cH:19][cH:20]2)[c:5]([C:8](=[O:9])[OH:10])[n:6][cH:7]1.[O:26]1[c:27]2[c:28]([n:32][cH:33][cH:34][cH:35]2)[NH:29][CH2:30][CH2:31]1>>[Cl:1][c:2]1[cH:3][c:4]([NH:11][S:12](=[O:13])(=[O:14])[c:15]2[cH:16][c:17]([C:22]([F:23])([F:24])[F:25])[c:18]([Cl:21])[cH:19][cH:20]2)[c:5]([C:8](=[O:9])[N:29]2[c:28]3[c:27]([cH:35][cH:34][cH:33][n:32]3)[O:26][CH2:31][CH2:30]2)[n:6][cH:7]1

Participants

4

Reactant 3

HCID 8471TriethylamineHCID 131965383,4-Dihydro-2H-pyrido(3,2-b)(1,4)oxazineHCID 579420775-Chloro-3-(4-chloro-3-trifluoromethyl benzenesulfonylamino)-pyridine-2-carboxylic acid

Product 1

HCID 441771844-chloro-N-[5-chloro-2-(2,3-dihydro-pyrido[3,2-b][1,4]oxazine-4-carbonyl)-pyridin-3-yl]-3-trifluoromethyl-benzenesulfonamide

Sources & evidence

ORD record
ord-06667efc58f34397a4bdb2fe1cd2c348
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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