Dichloromethane → 1,1-Dimethylethyl 4-[2-[[(methylsulfonyl)amino]methyl]phenyl]-1-piperazinecarboxylate

HRID 1140259Notes

Reaction equation

HRID 1140259 reaction equation
[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[c:15]([CH2:20][NH2:21])[cH:16][cH:17][cH:18][cH:19]2)[CH2:12][CH2:13]1.[CH2:34]([Cl:35])[Cl:36].[CH3:22][CH2:23][N:24]([CH2:25][CH3:26])[CH2:27][CH3:28].[CH3:29][S:30]([Cl:31])(=[O:32])=[O:33]>>[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[c:15]([CH2:20][NH:21][S:30]([CH3:29])(=[O:32])=[O:33])[cH:16][cH:17][cH:18][cH:19]2)[CH2:12][CH2:13]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 31297Methanesulfonyl chlorideHCID 4961274Tert-butyl 4-[2-(aminomethyl)phenyl]piperazine-1-carboxylate

Product 1

HCID 542677021,1-Dimethylethyl 4-[2-[[(methylsulfonyl)amino]methyl]phenyl]-1-piperazinecarboxylate

Sources & evidence

ORD record
ord-0df5ab04d33d4886b35ff0f7e50f9641
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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