Sodium ion → (+/-)-4-(3-chlorophenyl)-6-[hydroxy[4-(hydroxymethyl)phenyl](1-methyl-1H-imidazol-5-yl)methyl]-1-methyl-2(1H)-quinolinone

HRID 1140436Notes

Reaction equation

HRID 1140436 reaction equation
[BH4-:1].[CH2:39]1[O:40][CH2:41][CH2:42][CH2:43]1.[Cl:3][c:4]1[cH:5][c:6](-[c:10]2[cH:11][c:12](=[O:37])[n:13]([CH3:36])[c:14]3[cH:15][cH:16][c:17]([C:20]([c:21]4[cH:22][cH:23][c:24]([CH:25]=[O:26])[cH:27][cH:28]4)([c:29]4[cH:30][n:31][cH:32][n:33]4[CH3:34])[OH:35])[cH:18][c:19]23)[cH:7][cH:8][cH:9]1.[Na+:2].[OH2:38]>>[Cl:3][c:4]1[cH:5][c:6](-[c:10]2[cH:11][c:12](=[O:37])[n:13]([CH3:36])[c:14]3[cH:15][cH:16][c:17]([C:20]([c:21]4[cH:22][cH:23][c:24]([CH2:25][OH:26])[cH:27][cH:28]4)([c:29]4[cH:30][n:31][cH:32][n:33]4[CH3:34])[OH:35])[cH:18][c:19]23)[cH:7][cH:8][cH:9]1

Participants

6

Reactant 5

HCID 923Sodium ionHCID 962WaterHCID 8028TetrahydrofuranHCID 28123BorohydrideHCID 10299684(+/-)-4-[[4-(3-chlorophenyl)-1,2-dihydro-1-methyl-2-oxo-6-quinolinyl]hydroxy(1-methyl-1H-imidazol-5-yl)methyl]benzaldehyde

Product 1

HCID 10140969(+/-)-4-(3-chlorophenyl)-6-[hydroxy[4-(hydroxymethyl)phenyl](1-methyl-1H-imidazol-5-yl)methyl]-1-methyl-2(1H)-quinolinone

Sources & evidence

ORD record
ord-83aa738d8ee745a9b1a04f531e1aa764
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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