Diethyl Ether → 5-{[(2-Fluoro-4-methoxyphenyl)(2-trifluoromethyl-oxiranyl)methyl]amino}-1H-quinolin-2-one
Reaction equation
[CH2:40]1[O:41][CH2:42][CH2:43][CH2:44]1.[CH2:8]([Li:9])[CH2:10][CH2:11][CH3:12].[CH3:35][CH2:36][O:37][CH2:38][CH3:39].[CH3:45][CH2:46][CH2:47][CH2:48][CH2:49][CH3:50].[F:13][c:14]1[c:15]([CH:22]=[N:23][c:24]2[c:25]3[cH:26][cH:27][c:28](=[O:34])[nH:29][c:30]3[cH:31][cH:32][cH:33]2)[cH:16][cH:17][c:18]([O:20][CH3:21])[cH:19]1.[F:1][C:2]([CH:3]1[CH2:4][O:5]1)([F:6])[F:7]>>[F:1][C:2]([C:3]1([CH:22]([c:15]2[c:14]([F:13])[cH:19][c:18]([O:20][CH3:21])[cH:17][cH:16]2)[NH:23][c:24]2[c:25]3[cH:26][cH:27][c:28](=[O:34])[nH:29][c:30]3[cH:31][cH:32][cH:33]2)[CH2:4][O:5]1)([F:6])[F:7]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-cb795f2db637451f91b9034b17f0012b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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