Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1140900Generated: November 3, 2026

Diethyl Ether → Ethyl 2-[2-(2,4-difluorophenylamino)-5-fluoro-6-(2,4,6-trimethylbenzenesulfonyloxy)nicotinoyl]acetate

https://huagongshe.com/reaction/1140900

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethyl EtherHCID 3283—
ReactantDichloromethaneHCID 6344—
ReactantTriethylamineHCID 8471—
Reactant2-Mesitylenesulfonyl chlorideHCID 13046—
ReactantEthyl 2-[2-(2,4-difluorophenylamino)-5-fluoro-6-hydroxynicotinoyl]acetateHCID 178472175—
ProductEthyl 2-[2-(2,4-difluorophenylamino)-5-fluoro-6-(2,4,6-trimethylbenzenesulfonyloxy)nicotinoyl]acetateHCID 13849317—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-c4d5608b9a584be084fc60cd7bfe0b79
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)