Diethyl Ether → Ethyl 2-[2-(2,4-difluorophenylamino)-5-fluoro-6-(2,4,6-trimethylbenzenesulfonyloxy)nicotinoyl]acetate
Reaction equation
[CH2:51]([Cl:52])[Cl:53].[CH3:26][c:27]1[c:28]([S:35](=[O:36])(=[O:37])[Cl:38])[c:29]([CH3:34])[cH:30][c:31]([CH3:33])[cH:32]1.[CH3:39][CH2:40][N:41]([CH2:42][CH3:43])[CH2:44][CH3:45].[CH3:46][CH2:47][O:48][CH2:49][CH3:50].[F:1][c:2]1[c:3]([NH:9][c:10]2[c:11]([C:12](=[O:13])[CH2:14][C:15](=[O:16])[O:17][CH2:18][CH3:19])[cH:20][c:21]([F:25])[c:22]([OH:24])[n:23]2)[cH:4][cH:5][c:6]([F:8])[cH:7]1>>[F:1][c:2]1[c:3]([NH:9][c:10]2[c:11]([C:12](=[O:13])[CH2:14][C:15](=[O:16])[O:17][CH2:18][CH3:19])[cH:20][c:21]([F:25])[c:22]([O:24][S:35]([c:28]3[c:27]([CH3:26])[cH:32][c:31]([CH3:33])[cH:30][c:29]3[CH3:34])(=[O:36])=[O:37])[n:23]2)[cH:4][cH:5][c:6]([F:8])[cH:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-c4d5608b9a584be084fc60cd7bfe0b79
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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