Bicarbonate Ion → Benzyl 5-aminoisoindoline-2-carboxylate

HRID 1140951Notes

Reaction equation

HRID 1140951 reaction equation
[N+:1]([O-:2])(=[O:3])[c:4]1[cH:5][c:6]2[c:10]([cH:11][cH:12]1)[CH2:9][N:8]([C:13](=[O:14])[O:15][CH2:16][c:17]1[cH:18][cH:19][cH:20][cH:21][cH:22]1)[CH2:7]2.[Na+:27].[O-:23][C:24]([OH:25])=[O:26].[O:28]=[CH:29][N:30]([CH3:31])[CH3:32]>>[NH2:1][c:4]1[cH:5][c:6]2[c:10]([cH:11][cH:12]1)[CH2:9][N:8]([C:13](=[O:14])[O:15][CH2:16][c:17]1[cH:18][cH:19][cH:20][cH:21][cH:22]1)[CH2:7]2

Participants

5

Reactant 4

HCID 769Bicarbonate IonHCID 923Sodium ionHCID 6228DimethylformamideHCID 67057710benzyl 5-nitro-1,3-dihydro-2H-isoindole-2-carboxylate

Product 1

HCID 67057746Benzyl 5-aminoisoindoline-2-carboxylate

Sources & evidence

ORD record
ord-e01ef95bc1124d1f8426f8758a10ac9c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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