Sodium ion → 5-(2-chloro-4-fluorophenyl)-1-(2,6-dichlorophenyl)-7-[(5-isopropyl-2,5-diazabicyclo[2.2.1]hept-2-yl)methyl]-3,4-dihydroquinazolin-2(1H)-one
Reaction equation
[Cl:1][c:2]1[c:3](-[c:9]2[c:10]3[c:15]([cH:16][c:17]([CH2:19][N:20]4[CH:21]5[CH2:22][N:23]([CH:27]([CH3:28])[CH3:29])[CH:24]([CH2:25]4)[CH2:26]5)[cH:18]2)[N:14]([c:30]2[c:31]([Cl:37])[cH:32][cH:33][cH:34][c:35]2[Cl:36])[C:13](=[O:38])[N:12]([CH2:39][c:40]2[cH:41][cH:42][c:43]([O:44][CH3:45])[cH:46][cH:47]2)[CH2:11]3)[cH:4][cH:5][c:6]([F:8])[cH:7]1.[Na+:49].[OH-:48].[OH:50][C:51]([C:52]([F:53])([F:54])[F:55])=[O:56]>>[Cl:1][c:2]1[c:3](-[c:9]2[c:10]3[c:15]([cH:16][c:17]([CH2:19][N:20]4[CH:21]5[CH2:22][N:23]([CH:27]([CH3:28])[CH3:29])[CH:24]([CH2:25]4)[CH2:26]5)[cH:18]2)[N:14]([c:30]2[c:31]([Cl:37])[cH:32][cH:33][cH:34][c:35]2[Cl:36])[C:13](=[O:38])[NH:12][CH2:11]3)[cH:4][cH:5][c:6]([F:8])[cH:7]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-70bfa473e9374d858959bbc4ba610b36
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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