Ammonium → tert-butyl N-[(4-aminophenyl)methyl]carbamate

HRID 1141342Notes

Reaction equation

HRID 1141342 reaction equation
[CH3:19][CH2:20][OH:21].[Cl-:23].[N+:1]([O-:2])(=[O:3])[c:4]1[cH:5][cH:6][c:7]([CH2:8][NH:9][C:10]([O:11][C:12]([CH3:13])([CH3:14])[CH3:15])=[O:16])[cH:17][cH:18]1.[NH4+:24].[O:25]1[CH2:26][CH2:27][O:28][CH2:29][CH2:30]1.[OH2:22]>>[NH2:1][c:4]1[cH:5][cH:6][c:7]([CH2:8][NH:9][C:10]([O:11][C:12]([CH3:13])([CH3:14])[CH3:15])=[O:16])[cH:17][cH:18]1

Participants

7

Reactant 6

HCID 223AmmoniumHCID 312ChlorideHCID 702EthanolHCID 962WaterHCID 312751,4-DioxaneHCID 10610803tert-Butyl 4-nitrobenzylcarbamate

Product 1

HCID 2756041tert-butyl N-[(4-aminophenyl)methyl]carbamate

Sources & evidence

ORD record
ord-c6e2b3a9be234b11bc8284e09b0a5665
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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