Methyl Acrylate → methyl 3-(4-oxo-1'-phenylspiro[3H-chromene-2,4'-piperidine]-6-yl)prop-2-enoate

HRID 1141422Notes

Reaction equation

HRID 1141422 reaction equation
[C:24]([CH:25]=[CH2:26])(=[O:27])[O:28][CH3:29].[CH3:30][O:31][C:32](=[O:33])[CH:34]=[CH:35][c:36]1[cH:37][c:38]2[c:39]([cH:40][cH:41]1)[O:42][C:43]1([CH2:44][CH2:45][N:46]([C:47]([O:48][C:49]([CH3:50])([CH3:51])[CH3:52])=[O:53])[CH2:54][CH2:55]1)[CH2:56][C:57]2=[O:58].[c:1]1([N:7]2[CH2:8][CH2:9][C:10]3([O:11][c:12]4[cH:13][cH:14][c:15]([Br:21])[cH:16][c:17]4[C:18](=[O:20])[CH2:19]3)[CH2:22][CH2:23]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([N:7]2[CH2:8][CH2:9][C:10]3([O:11][c:12]4[cH:13][cH:14][c:15]([CH:26]=[CH:25][C:24](=[O:27])[O:28][CH3:29])[cH:16][c:17]4[C:18](=[O:20])[CH2:19]3)[CH2:22][CH2:23]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

4

Reactant 3

HCID 7294Methyl AcrylateHCID 669322201'-Phenyl-6-bromo-spiro[chromane-2,4'-piperidine]-4-oneHCID 66932397tert-butyl 6-(3-methoxy-3-oxoprop-1-enyl)-4-oxospiro[3H-chromene-2,4'-piperidine]-1'-carboxylate

Product 1

HCID 66932531methyl 3-(4-oxo-1'-phenylspiro[3H-chromene-2,4'-piperidine]-6-yl)prop-2-enoate

Sources & evidence

ORD record
ord-36f4d927c2f940449bd8fb74e2bbf4bb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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