Bromide ion → 4-(2,2-dimethylpropyl)-2-{2-fluoro-2-[4-(5-fluoropyridin-2-yl)phenyl]-1-hydroxy-1-methylethyl}-N,N-dimethyl-1H-imidazole-1-sulfonamide
Reaction equation
[Br-:1].[CH3:2][Mg+:3].[CH3:4][C:5]([CH2:6][c:7]1[n:8][c:9]([C:18]([CH:19]([c:20]2[cH:21][cH:22][c:23](-[c:26]3[n:27][cH:28][c:29]([F:32])[cH:30][cH:31]3)[cH:24][cH:25]2)[F:33])=[O:34])[n:10]([S:12](=[O:13])(=[O:14])[N:15]([CH3:16])[CH3:17])[cH:11]1)([CH3:35])[CH3:36].[O:37]1[CH2:38][CH2:39][CH2:40][CH2:41]1>>[CH3:2][C:18]([c:9]1[n:8][c:7]([CH2:6][C:5]([CH3:4])([CH3:35])[CH3:36])[cH:11][n:10]1[S:12](=[O:13])(=[O:14])[N:15]([CH3:16])[CH3:17])([CH:19]([c:20]1[cH:21][cH:22][c:23](-[c:26]2[n:27][cH:28][c:29]([F:32])[cH:30][cH:31]2)[cH:24][cH:25]1)[F:33])[OH:34]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-ac65c491cf454a1eadbad2fae7fc4b43
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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