1,2-Dichloroethane → 4-{[(2,4-Dichloro-thiazol-5-yl)methyl]-amino}-piperidine-1-carboxylic acid t-butyl ester
Reaction equation
[C:15]([CH3:16])([CH3:17])([CH3:18])[O:19][C:20](=[O:21])[N:22]1[CH2:23][CH2:24][CH:25]([NH2:28])[CH2:26][CH2:27]1.[C:1]([O:2][BH-:3]([O:4][C:5](=[O:6])[CH3:7])[O:8][C:9](=[O:10])[CH3:11])(=[O:12])[CH3:13].[CH3:38][C:39](=[O:40])[OH:41].[Cl:29][c:30]1[s:31][c:32]([CH:36]=[O:37])[c:33]([Cl:35])[n:34]1.[Cl:44][CH2:45][CH2:46][Cl:47].[Na+:14].[Na+:43].[OH-:42]>>[C:15]([CH3:16])([CH3:17])([CH3:18])[O:19][C:20](=[O:21])[N:22]1[CH2:23][CH2:24][CH:25]([NH:28][CH2:36][c:32]2[s:31][c:30]([Cl:29])[n:34][c:33]2[Cl:35])[CH2:26][CH2:27]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-e5d1dfcc86324574b426c8357a6d0469
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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