Dimethylformamide → 5-fluoro-3-[1-(2-(4-pyridinyl)acetyl)-4-piperidinyl]-1H-indole

HRID 1141699Notes

Reaction equation

HRID 1141699 reaction equation
[CH3:37][N:38]([CH3:39])[CH:40]=[O:41].[F:1][c:2]1[cH:3][c:4]2[c:5]([CH:11]3[CH2:12][CH2:13][NH:14][CH2:15][CH2:16]3)[cH:6][nH:7][c:8]2[cH:9][cH:10]1.[n:17]1[cH:18][cH:19][c:20]([CH2:23][C:24](=[O:25])[O:26][O:27][c:28]2[c:29]([Cl:30])[cH:31][c:32]([Cl:33])[c:34]([Cl:35])[cH:36]2)[cH:21][cH:22]1>>[F:1][c:2]1[cH:3][c:4]2[c:5]([CH:11]3[CH2:12][CH2:13][N:14]([C:24]([CH2:23][c:20]4[cH:19][cH:18][n:17][cH:22][cH:21]4)=[O:25])[CH2:15][CH2:16]3)[cH:6][nH:7][c:8]2[cH:9][cH:10]1

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 117699295-fluoro-3-(piperidin-4-yl)-1H-indoleHCID 196965283,4,6-Trichlorophenoxy 2-(4-pyridinyl)acetate

Product 1

HCID 196965245-fluoro-3-[1-(2-(4-pyridinyl)acetyl)-4-piperidinyl]-1H-indole

Sources & evidence

ORD record
ord-4dc0e36d85f04255be630dc142dcfe55
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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