HRID1141722

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID8028

Tetrahydrofuran

C4H8O

HCID10868

Dicyclohexylcarbodiimide

C13H22N2

HCID415852

1-Benzyl-4-piperidinylamine

C12H18N2

HCID13536275

5-Fluoro-2-methyl-1H-indole-3-carboxylic acid

C10H8FNO2

PRODUCTS

生成物

结构：Cc1[nH]c2ccc(F)cc2c1C(=O)NC1CCN(Cc2ccccc2)CC1

HCID3062667

1H-Indole-3-carboxamide, 5-fluoro-2-methyl-N-(1-(phenylmethyl)-4-piperidinyl)-

C22H24FN3O

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-5bb63df442da4129bcf3eb444aea70d5
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D
来源说明: Training data from https://doi.org/10.1039/C8SC04228D (7/10)

反应 SMILES

[CH:29]1([N:30]=[C:31]=[N:32][CH:33]2[CH2:34][CH2:35][CH2:36][CH2:37][CH2:38]2)[CH2:39][CH2:40][CH2:41][CH2:42][CH2:43]1.[F:1][c:2]1[cH:3][c:4]2[c:5]([C:12](=[O:13])[OH:14])[c:6]([CH3:11])[nH:7][c:8]2[cH:9][cH:10]1.[NH2:15][CH:16]1[CH2:17][CH2:18][N:19]([CH2:22][c:23]2[cH:24][cH:25][cH:26][cH:27][cH:28]2)[CH2:20][CH2:21]1.[O:44]1[CH2:45][CH2:46][CH2:47][CH2:48]1>>[F:1][c:2]1[cH:3][c:4]2[c:5]([C:12](=[O:14])[NH:15][CH:16]3[CH2:17][CH2:18][N:19]([CH2:22][c:23]4[cH:24][cH:25][cH:26][cH:27][cH:28]4)[CH2:20][CH2:21]3)[c:6]([CH3:11])[nH:7][c:8]2[cH:9][cH:10]1