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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1141780Generated: October 26, 2026

Tetrahydrofuran → 2-[[2-Fluoro-4-(trifluoromethyl)phenyl]methyl]-3,6-dimethoxy-5-propan-2-yl-2,5-dihydropyrazine

https://huagongshe.com/reaction/1141780

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
Reactant2-Fluoro-4-(trifluoromethyl)benzyl bromideHCID 2737570—
Reactant2,5-Dihydro-2-isopropyl-3,6-dimethoxypyrazineHCID 3800909—
ReactantButyllithiumHCID 178418339—
Product2-[[2-Fluoro-4-(trifluoromethyl)phenyl]methyl]-3,6-dimethoxy-5-propan-2-yl-2,5-dihydropyrazineHCID 21911212—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-de97c9a1368b4eb5a24783f80d747c1b
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)