Trimethyl phosphite → [5-(2-Ethylbenzoimidazol-1-yl)-7-morpholin-4-ylthiazolo[5,4-d]pyrimidin-2-ylmethyl]phosphonic acid dimethyl ester

HRID 1141794Notes

Reaction equation

HRID 1141794 reaction equation
[Br:1][CH2:2][c:3]1[s:4][c:5]2[n:6][c:7](-[n:18]3[c:19]([CH2:27][CH3:28])[n:20][c:21]4[c:22]3[cH:23][cH:24][cH:25][cH:26]4)[n:8][c:9]([N:12]3[CH2:13][CH2:14][O:15][CH2:16][CH2:17]3)[c:10]2[n:11]1.[CH3:29][O:30][P:31]([O:32][CH3:33])[O:34][CH3:35]>>[CH2:2]([c:3]1[s:4][c:5]2[n:6][c:7](-[n:18]3[c:19]([CH2:27][CH3:28])[n:20][c:21]4[c:22]3[cH:23][cH:24][cH:25][cH:26]4)[n:8][c:9]([N:12]3[CH2:13][CH2:14][O:15][CH2:16][CH2:17]3)[c:10]2[n:11]1)[P:31]([O:30][CH3:29])([O:32][CH3:33])=[O:34]

Participants

3

Reactant 2

HCID 8472Trimethyl phosphiteHCID 596061112-Bromomethyl-5-(2-ethylbenzoimidazol-1-yl)-7-morpholin-4-ylthiazolo[5,4-d]pyrimidine

Product 1

HCID 59606043[5-(2-Ethylbenzoimidazol-1-yl)-7-morpholin-4-ylthiazolo[5,4-d]pyrimidin-2-ylmethyl]phosphonic acid dimethyl ester

Sources & evidence

ORD record
ord-ccd60f88432547dab9deb9c8e30bc435
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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