Hydrogen Peroxide → 7-(2-Fluoro-4-methylsulfinylphenyl)-4-[1-(5-fluoropyrimidin-2-yl)piperidin-4-yl]oxy-5,6-dihydropyrrolo[2,3-d]pyrimidine

HRID 1141820Notes

Reaction equation

HRID 1141820 reaction equation
[F:1][c:2]1[c:3]([N:10]2[CH2:11][CH2:12][c:13]3[c:14]2[n:15][cH:16][n:17][c:18]3[O:19][CH:20]2[CH2:21][CH2:22][N:23]([c:26]3[n:27][cH:28][c:29]([F:32])[cH:30][n:31]3)[CH2:24][CH2:25]2)[cH:4][cH:5][c:6]([S:8][CH3:9])[cH:7]1.[F:35][C:36]([F:37])([F:38])[CH:39]([OH:40])[C:41]([F:42])([F:43])[F:44].[OH:33][OH:34]>>[F:1][c:2]1[c:3]([N:10]2[CH2:11][CH2:12][c:13]3[c:14]2[n:15][cH:16][n:17][c:18]3[O:19][CH:20]2[CH2:21][CH2:22][N:23]([c:26]3[n:27][cH:28][c:29]([F:32])[cH:30][n:31]3)[CH2:24][CH2:25]2)[cH:4][cH:5][c:6]([S:8]([CH3:9])=[O:33])[cH:7]1

Participants

4

Reactant 3

HCID 784Hydrogen PeroxideHCID 135291,1,1,3,3,3-Hexafluoro-2-propanolHCID 248989877-(2-Fluoro-4-methylsulfanylphenyl)-4-[1-(5-fluoropyrimidin-2-yl)piperidin-4-yl]oxy-5,6-dihydropyrrolo[2,3-d]pyrimidine

Product 1

HCID 248989887-(2-Fluoro-4-methylsulfinylphenyl)-4-[1-(5-fluoropyrimidin-2-yl)piperidin-4-yl]oxy-5,6-dihydropyrrolo[2,3-d]pyrimidine

Sources & evidence

ORD record
ord-3e061e3252904a9e9a6410795b61d2cb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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