4-Methoxybenzylamine → 7-(4-methoxybenzylamino)-3-(3-amino-4-fluorophenyl)-1-methyl-3,4-dihydropyrido[4,3-d]pyrimidin-2(1H)-one

HRID 1141944Notes

Reaction equation

HRID 1141944 reaction equation
[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH2:7][NH2:8])[cH:9][cH:10]1.[NH2:11][c:12]1[cH:13][c:14]([N:19]2[C:20](=[O:31])[N:21]([CH3:30])[c:22]3[c:23]([cH:25][n:26][c:27]([Cl:29])[cH:28]3)[CH2:24]2)[cH:15][cH:16][c:17]1[F:18]>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH2:7][NH:8][c:27]2[n:26][cH:25][c:23]3[c:22]([cH:28]2)[N:21]([CH3:30])[C:20](=[O:31])[N:19]([c:14]2[cH:13][c:12]([NH2:11])[c:17]([F:18])[cH:16][cH:15]2)[CH2:24]3)[cH:9][cH:10]1

Participants

3

Reactant 2

HCID 754524-MethoxybenzylamineHCID 866294573-(3-amino-4-fluorophenyl)-7-chloro-1-methyl-3,4-dihydropyrido[4,3-d]pyrimidin-2(1H)-one

Product 1

HCID 670630727-(4-methoxybenzylamino)-3-(3-amino-4-fluorophenyl)-1-methyl-3,4-dihydropyrido[4,3-d]pyrimidin-2(1H)-one

Sources & evidence

ORD record
ord-ccfd2f4f1e1046b2af201da889939d16
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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