Methyl iodide → Basimglurant

HRID 1142186Notes

Reaction equation

HRID 1142186 reaction equation
[CH2:25]1[O:26][CH2:27][CH2:28][CH2:29]1.[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]([C:8]#[C:9][c:10]2[n:11][c:12]([CH3:22])[n:13](-[c:15]3[cH:16][cH:17][c:18]([F:21])[cH:19][cH:20]3)[cH:14]2)[cH:7]1.[I:23][CH3:24]>>[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]([C:8]#[C:9][c:10]2[n:11][c:12]([CH3:22])[n:13](-[c:15]3[cH:16][cH:17][c:18]([F:21])[cH:19][cH:20]3)[c:14]2[CH3:24])[cH:7]1

Participants

4

Reactant 3

HCID 6328Methyl iodideHCID 8028TetrahydrofuranHCID 112783692-Chloro-4-[1-(4-fluoro-phenyl)-2-methyl-1H-imidazol-4-ylethynyl]-pyridine

Product 1

HCID 11438771Basimglurant

Sources & evidence

ORD record
ord-de5199776ad848bc9efec2e2d9226d1f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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