Imidazole → 3-[Tert-butyl(dimethyl)silyl]oxy-1-(4-imidazol-1-ylbut-2-ynyl)pyrrolidin-2-one
Reaction equation
[Br:1][CH2:2][C:3]#[C:4][CH2:5][N:6]1[C:7](=[O:19])[CH:8]([O:11][Si:12]([CH3:13])([CH3:14])[C:15]([CH3:16])([CH3:17])[CH3:18])[CH2:9][CH2:10]1.[O:25]1[CH2:26][CH2:27][CH2:28][CH2:29]1.[nH:20]1[cH:21][n:22][cH:23][cH:24]1>>[CH2:2]([C:3]#[C:4][CH2:5][N:6]1[C:7](=[O:19])[CH:8]([O:11][Si:12]([CH3:13])([CH3:14])[C:15]([CH3:16])([CH3:17])[CH3:18])[CH2:9][CH2:10]1)[n:20]1[cH:21][n:22][cH:23][cH:24]1Participants
4
Sources & evidence
- ORD record
- ord-72f89b763d4041f087011ee1272dbfaa
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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