Hydrogen Bromide → {2-[6-(2-Ethyl-5-fluoro-4-hydroxy-phenyl)-1H-indazol-3-yl]-1,4,6,7-tetrahydro-imidazo[4,5-c]pyridin-5-yl}-isothiazol-3-yl-methanone

HRID 1142863Notes

Reaction equation

HRID 1142863 reaction equation
[BrH:1].[BrH:2].[BrH:3].[CH2:4]([CH3:5])[c:6]1[c:7](-[c:14]2[cH:15][cH:16][c:17]3[c:18](-[c:23]4[nH:24][c:25]5[c:26]([n:31]4)[CH2:27][NH:28][CH2:29][CH2:30]5)[n:19][nH:20][c:21]3[cH:22]2)[cH:8][c:9]([F:13])[c:10]([OH:12])[cH:11]1.[s:32]1[n:33][c:34]([C:37](=[O:38])[OH:39])[cH:35][cH:36]1>>[CH2:4]([CH3:5])[c:6]1[c:7](-[c:14]2[cH:15][cH:16][c:17]3[c:18](-[c:23]4[nH:24][c:25]5[c:26]([n:31]4)[CH2:27][N:28]([C:37]([c:34]4[n:33][s:32][cH:36][cH:35]4)=[O:38])[CH2:29][CH2:30]5)[n:19][nH:20][c:21]3[cH:22]2)[cH:8][c:9]([F:13])[c:10]([OH:12])[cH:11]1

Participants

4

Reactant 3

HCID 260Hydrogen Bromide3×HCID 5592241,2-Thiazole-3-carboxylic acidHCID 178436901HCID 178436901, compound

Product 1

HCID 178436918{2-[6-(2-Ethyl-5-fluoro-4-hydroxy-phenyl)-1H-indazol-3-yl]-1,4,6,7-tetrahydro-imidazo[4,5-c]pyridin-5-yl}-isothiazol-3-yl-methanone

Sources & evidence

ORD record
ord-2b8776d00d644095ad48c7fe3d70f231
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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