Methanol → 2-(2-Bromoisonicotinoylamino)-3-(3,4-dimethoxyphenyl)-1-propanol

HRID 1143103Notes

Reaction equation

[Br:1][c:2]1[cH:3][c:4]([C:32]([O:7][CH2:8][CH:9]([CH2:10][c:11]2[cH:12][c:13]([O:19][CH3:20])[c:14]([O:17][CH3:18])[cH:15][cH:16]2)[NH:21][C:22]([c:23]2[cH:24][c:25]([Br:29])[n:26][cH:27][cH:28]2)=[O:30])=[O:33])[cH:5][cH:6][n:31]1.[CH3:36][OH:37].[Li+:34].[OH-:35]>>[OH:7][CH2:8][CH:9]([CH2:10][c:11]1[cH:12][c:13]([O:19][CH3:20])[c:14]([O:17][CH3:18])[cH:15][cH:16]1)[NH:21][C:22]([c:23]1[cH:24][c:25]([Br:29])[n:26][cH:27][cH:28]1)=[O:30]

Participants

Reactant 4

HCID 887Methanol

HCID 961Hydroxide

HCID 28486Lithium ion

HCID 178490178[2-[(2-bromopyridine-4-carbonyl)amino]-3-(3,4-dimethoxyphenyl)propyl] 2-bromopyridine-4-carboxylate

Product 1

HCID 218408112-(2-Bromoisonicotinoylamino)-3-(3,4-dimethoxyphenyl)-1-propanol

Sources & evidence

ORD record: ord-a5a8477a9099466a9a4cfa538859e3b0
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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