2,4-Dichloro-5-fluoropyrimidine → 2-chloro-4-cyclopropyl-5-fluoroPyrimidine

HRID 1143153Notes

Reaction equation

HRID 1143153 reaction equation
[CH:10]1([B:13]([OH:14])[OH:15])[CH2:11][CH2:12]1.[F:1][c:2]1[c:3]([Cl:9])[n:4][c:5]([Cl:8])[n:6][cH:7]1>>[F:1][c:2]1[c:3]([CH:10]2[CH2:11][CH2:12]2)[n:4][c:5]([Cl:8])[n:6][cH:7]1

Participants

3

Reactant 2

HCID 2507052,4-Dichloro-5-fluoropyrimidineHCID 2760897Cyclopropylboronic acid

Product 1

HCID 772310692-chloro-4-cyclopropyl-5-fluoroPyrimidine

Sources & evidence

ORD record
ord-501a854ae09a4027b9c3c10e5d0ce8c6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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