Dichloromethane → Dimethyl 2-(4-fluorobenzyl)piperidine-1,4-dicarboxylate

HRID 1143365Notes

Reaction equation

HRID 1143365 reaction equation
[C:28]([O:29][CH3:30])(=[O:31])[Cl:32].[CH:19]([N:20]([CH2:21][CH3:22])[CH:23]([CH3:24])[CH3:25])([CH3:26])[CH3:27].[Cl:33][CH2:34][Cl:35].[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][CH:7]2[NH:8][CH2:9][CH2:10][CH:11]([C:13](=[O:14])[O:15][CH3:16])[CH2:12]2)[cH:17][cH:18]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][CH:7]2[N:8]([C:28]([O:29][CH3:30])=[O:31])[CH2:9][CH2:10][CH:11]([C:13](=[O:14])[O:15][CH3:16])[CH2:12]2)[cH:17][cH:18]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 6586Methyl chloroformateHCID 81531DiisopropylethylamineHCID 66731633HCID 66731633, compound

Product 1

HCID 66735290Dimethyl 2-(4-fluorobenzyl)piperidine-1,4-dicarboxylate

Sources & evidence

ORD record
ord-32ff4b24ebb343fcab5e9446f1cb8623
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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