Tetrahydrofuran → 3-[1-[2-Fluoro-4-(trifluoromethyl)phenyl]-3-azabicyclo[3.1.0]hexan-3-yl]propan-1-ol
Reaction equation
[CH2:29]1[O:30][CH2:31][CH2:32][CH2:33]1.[CH3:1][C:2]([Si:3]([CH3:4])([CH3:5])[O:6][CH2:7][CH2:8][CH2:9][N:10]1[CH2:11][C:12]2([c:16]3[c:17]([F:26])[cH:18][c:19]([C:22]([F:23])([F:24])[F:25])[cH:20][cH:21]3)[CH2:13][CH:14]2[CH2:15]1)([CH3:27])[CH3:28]>>[OH:6][CH2:7][CH2:8][CH2:9][N:10]1[CH2:11][C:12]2([c:16]3[c:17]([F:26])[cH:18][c:19]([C:22]([F:23])([F:24])[F:25])[cH:20][cH:21]3)[CH2:13][CH:14]2[CH2:15]1Participants
3
Sources & evidence
- ORD record
- ord-2b16cdf64add4180b815f9e243dbf2d5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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