Dichloromethane → trans-1-(4-Benzo[d]isothiazol-3-yl-cyclohexyl)-8-chloro-5-methanesulfonyl-5,6-dihydro-4H-2,3,5,10b-tetraaza-benzo[e]azulene

HRID 1143621Notes

Reaction equation

HRID 1143621 reaction equation
[CH3:31][CH2:32][N:33]([CH2:34][CH3:35])[CH2:36][CH3:37].[CH3:38][S:39]([Cl:40])(=[O:41])=[O:42].[Cl:43][CH2:44][Cl:45].[s:1]1[n:2][c:3]([CH:10]2[CH2:11][CH2:12][CH:13]([c:16]3[n:17][n:18][c:19]4[n:25]3-[c:24]3[c:23]([cH:29][c:28]([Cl:30])[cH:27][cH:26]3)[CH2:22][NH:21][CH2:20]4)[CH2:14][CH2:15]2)[c:4]2[c:5]1[cH:6][cH:7][cH:8][cH:9]2>>[s:1]1[n:2][c:3]([CH:10]2[CH2:11][CH2:12][CH:13]([c:16]3[n:17][n:18][c:19]4[n:25]3-[c:24]3[c:23]([cH:29][c:28]([Cl:30])[cH:27][cH:26]3)[CH2:22][N:21]([S:39]([CH3:38])(=[O:41])=[O:42])[CH2:20]4)[CH2:14][CH2:15]2)[c:4]2[c:5]1[cH:6][cH:7][cH:8][cH:9]2

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 31297Methanesulfonyl chlorideHCID 54577735HCID 54577735, compound

Product 1

HCID 54577955trans-1-(4-Benzo[d]isothiazol-3-yl-cyclohexyl)-8-chloro-5-methanesulfonyl-5,6-dihydro-4H-2,3,5,10b-tetraaza-benzo[e]azulene

Sources & evidence

ORD record
ord-94b9cb73e9d74a5481b1db903fc87d0c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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