Dichloromethane → 4-Chloro-6-methoxy-7-[3-(4-prop-2-yn-1-ylpiperazin-1-yl)propoxy]quinazoline
Reaction equation
[CH2:34]([C:35]#[CH:36])[N:37]1[CH2:38][CH2:39][N:40]([CH2:43][CH2:44][CH2:45][OH:46])[CH2:41][CH2:42]1.[Cl:1][c:2]1[n:3][cH:4][n:5][c:6]2[cH:7][c:8]([OH:14])[c:9]([O:12][CH3:13])[cH:10][c:11]12.[Cl:47][CH2:48][Cl:49].[c:15]1([P:16]([c:17]2[cH:18][cH:19][cH:20][cH:21][cH:22]2)[c:23]2[cH:24][cH:25][cH:26][cH:27][cH:28]2)[cH:29][cH:30][cH:31][cH:32][cH:33]1>>[Cl:1][c:2]1[n:3][cH:4][n:5][c:6]2[cH:7][c:8]([O:14][CH2:45][CH2:44][CH2:43][N:40]3[CH2:39][CH2:38][N:37]([CH2:34][C:35]#[CH:36])[CH2:42][CH2:41]3)[c:9]([O:12][CH3:13])[cH:10][c:11]12Participants
5
Sources & evidence
- ORD record
- ord-ae202417a07749d689a16de6a240debe
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
Loading…