Benzene → Methyl 2-(1-tert-Butoxycarbonylpiperidin-4-yloxy)-4-fluorobenzoate
Reaction equation
[C:32]([CH3:33])([CH3:34])([CH3:35])[O:36][C:37](=[O:38])[N:39]1[CH2:40][CH2:41][CH:42]([OH:45])[CH2:43][CH2:44]1.[Cl:58][CH2:59][Cl:60].[F:1][c:2]1[cH:3][c:4]([OH:12])[c:5]([C:6](=[O:7])[O:8][CH3:9])[cH:10][cH:11]1.[O:46]=[C:47]([O:48][CH2:49][CH3:50])[N:51]=[N:52][C:53]([O:54][CH2:55][CH3:56])=[O:57].[c:13]1([P:14]([c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)[cH:27][cH:28][cH:29][cH:30][cH:31]1.[cH:61]1[cH:62][cH:63][cH:64][cH:65][cH:66]1>>[F:1][c:2]1[cH:3][c:4]([O:12][CH:42]2[CH2:41][CH2:40][N:39]([C:37]([O:36][C:32]([CH3:33])([CH3:34])[CH3:35])=[O:38])[CH2:44][CH2:43]2)[c:5]([C:6](=[O:7])[O:8][CH3:9])[cH:10][cH:11]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-2a5db428fbab4140a8f4b9e7956a53f2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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