Hydrochloric Acid → 3-Fluoro-4-(5-(1-phenylcyclohexyl)thiazolo[5,4-b]pyridine-2-yl)benzaldehyde

HRID 1143989Notes

Reaction equation

HRID 1143989 reaction equation
[ClH:35].[Na+:37].[O:1]1[CH:2]([c:7]2[cH:8][c:9]([F:34])[c:10](-[c:13]3[s:14][c:15]4[n:16][c:17]([C:22]5([c:28]6[cH:29][cH:30][cH:31][cH:32][cH:33]6)[CH2:23][CH2:24][CH2:25][CH2:26][CH2:27]5)[cH:18][cH:19][c:20]4[n:21]3)[cH:11][cH:12]2)[O:6][CH2:5][CH2:4][CH2:3]1.[OH-:36]>>[O:1]=[CH:2][c:7]1[cH:8][c:9]([F:34])[c:10](-[c:13]2[s:14][c:15]3[n:16][c:17]([C:22]4([c:28]5[cH:29][cH:30][cH:31][cH:32][cH:33]5)[CH2:23][CH2:24][CH2:25][CH2:26][CH2:27]4)[cH:18][cH:19][c:20]3[n:21]2)[cH:11][cH:12]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 923Sodium ionHCID 961HydroxideHCID 671117162-(4-(1,3-Dioxan-2-yl)-2-fluorophenyl)-5-(1-phenylcyclohexyl)thiazolo[5,4-b]pyridine

Product 1

HCID 866387093-Fluoro-4-(5-(1-phenylcyclohexyl)thiazolo[5,4-b]pyridine-2-yl)benzaldehyde

Sources & evidence

ORD record
ord-8cd2dd30f0c64cbf887e73f6cad6e8db
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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