Acetonitrile → tert-butyl 3-[fluoro(phenylsulfonyl)methyl]-3-[4-(7-{[2-(trimethylsilyl)ethoxy]methyl}-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]azetidine-1-carboxylate
Reaction equation
[CH3:56][C:57]#[N:58].[F:23][C:24]([S:25](=[O:26])(=[O:27])[c:28]1[cH:29][cH:30][cH:31][cH:32][cH:33]1)=[C:34]1[CH2:35][N:36]([C:38](=[O:39])[O:40][C:41]([CH3:42])([CH3:43])[CH3:44])[CH2:37]1.[N:45]12[CH2:46][CH2:47][CH2:48][N:49]=[C:50]1[CH2:51][CH2:52][CH2:53][CH2:54][CH2:55]2.[nH:1]1[n:2][cH:3][c:4](-[c:6]2[c:7]3[c:8]([n:9][cH:10][n:11]2)[n:12]([CH2:15][O:16][CH2:17][CH2:18][Si:19]([CH3:20])([CH3:21])[CH3:22])[cH:13][cH:14]3)[cH:5]1>>[n:1]1([C:34]2([CH:24]([F:23])[S:25](=[O:26])(=[O:27])[c:28]3[cH:29][cH:30][cH:31][cH:32][cH:33]3)[CH2:35][N:36]([C:38](=[O:39])[O:40][C:41]([CH3:42])([CH3:43])[CH3:44])[CH2:37]2)[n:2][cH:3][c:4](-[c:6]2[c:7]3[c:8]([n:9][cH:10][n:11]2)[n:12]([CH2:15][O:16][CH2:17][CH2:18][Si:19]([CH3:20])([CH3:21])[CH3:22])[cH:13][cH:14]3)[cH:5]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-979b00cd829a4603a1547eca699f6589
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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