Acetonitrile → N4-Acetyl-N1-(1-cyclopropylmethyl-1,2-dihydro-2-oxo-4-pyrimidinyl)sulfanilamide

HRID 1144001Notes

Reaction equation

HRID 1144001 reaction equation
[C:13]([CH3:14])(=[O:15])[NH:16][c:17]1[cH:18][cH:19][c:20]([S:21](=[O:22])(=[O:23])[Cl:24])[cH:25][cH:26]1.[CH3:27][C:28]#[N:29].[CH3:30][CH2:31][N:32]([CH2:33][CH3:34])[CH2:35][CH3:36].[CH:1]1([CH2:4][n:5]2[c:6](=[O:7])[n:8][c:9]([NH2:10])[cH:11][cH:12]2)[CH2:2][CH2:3]1>>[CH:1]1([CH2:4][n:5]2[c:6](=[O:7])[n:8][c:9]([NH:10][S:21]([c:20]3[cH:19][cH:18][c:17]([NH:16][C:13]([CH3:14])=[O:15])[cH:26][cH:25]3)(=[O:22])=[O:23])[cH:11][cH:12]2)[CH2:2][CH2:3]1

Participants

5

Reactant 4

HCID 6342AcetonitrileHCID 8471TriethylamineHCID 8481N-Acetylsulfanilyl chlorideHCID 214443201-Cyclopropylmethylcytosine

Product 1

HCID 86734625N4-Acetyl-N1-(1-cyclopropylmethyl-1,2-dihydro-2-oxo-4-pyrimidinyl)sulfanilamide

Sources & evidence

ORD record
ord-86c317b294eb42faa10d3cdfafc7d938
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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