3-Amino-1-propanol → 3-({4-[(1-{2-(Dimethylamino)-6-[2-(dimethylamino)ethoxy]benzyl}piperidin-4-yl)amino]-6,7-dimethoxyquinazolin-2-yl}amino)propan-1-ol
Reaction equation
[Cl:1][c:2]1[n:3][c:4]2[cH:5][c:6]([O:37][CH3:38])[c:7]([O:35][CH3:36])[cH:8][c:9]2[c:10]([NH:12][CH:13]2[CH2:14][CH2:15][N:16]([CH2:19][c:20]3[c:21]([N:32]([CH3:33])[CH3:34])[cH:22][cH:23][cH:24][c:25]3[O:26][CH2:27][CH2:28][N:29]([CH3:30])[CH3:31])[CH2:17][CH2:18]2)[n:11]1.[NH2:39][CH2:40][CH2:41][CH2:42][OH:43]>>[c:2]1([NH:39][CH2:40][CH2:41][CH2:42][OH:43])[n:3][c:4]2[cH:5][c:6]([O:37][CH3:38])[c:7]([O:35][CH3:36])[cH:8][c:9]2[c:10]([NH:12][CH:13]2[CH2:14][CH2:15][N:16]([CH2:19][c:20]3[c:21]([N:32]([CH3:33])[CH3:34])[cH:22][cH:23][cH:24][c:25]3[O:26][CH2:27][CH2:28][N:29]([CH3:30])[CH3:31])[CH2:17][CH2:18]2)[n:11]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-8b52c8f8acf94da9b8b6410a4d460801
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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