2-Bromobenzonitrile → 2-{4-[3-(3,5-Difluorophenyl)prop-2-yn-1-yl]piperidin-1-yl}benzonitrile
Reaction equation
[Br:18][c:19]1[c:20]([C:21]#[N:22])[cH:23][cH:24][cH:25][cH:26]1.[F:1][c:2]1[cH:3][c:4]([C:9]#[C:10][CH2:11][CH:12]2[CH2:13][CH2:14][NH:15][CH2:16][CH2:17]2)[cH:5][c:6]([F:8])[cH:7]1>>[F:1][c:2]1[cH:3][c:4]([C:9]#[C:10][CH2:11][CH:12]2[CH2:13][CH2:14][N:15]([c:19]3[c:20]([C:21]#[N:22])[cH:23][cH:24][cH:25][cH:26]3)[CH2:16][CH2:17]2)[cH:5][c:6]([F:8])[cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-2e93f5035d2043ce8586a8e4d3389a61
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
Loading…