Hydrochloric Acid → 3-(4-piperidinyl)-5-(3-thienyl)-1H-indole-7-carboxamide

HRID 1144411Notes

Reaction equation

HRID 1144411 reaction equation
[CH3:55][OH:56].[ClH:54].[NH2:24][C:25](=[O:26])[c:27]1[cH:28][c:29](-[c:49]2[cH:50][s:51][cH:52][cH:53]2)[cH:30][c:31]2[c:32]([CH:36]3[CH2:37][CH2:38][N:39]([C:42]([O:43][C:44]([CH3:45])([CH3:46])[CH3:47])=[O:48])[CH2:40][CH2:41]3)[cH:33][nH:34][c:35]12.[NH:1]1[CH2:2][CH2:3][CH:4]([c:5]2[c:6]3[c:7]([c:8]([C:9]([NH2:10])=[O:11])[cH:12][c:13](-[c:14]4[s:15][cH:16][cH:17][cH:18]4)[cH:19]3)[nH:20][cH:21]2)[CH2:22][CH2:23]1>>[NH2:24][C:25](=[O:26])[c:27]1[cH:28][c:29](-[c:49]2[cH:50][s:51][cH:52][cH:53]2)[cH:30][c:31]2[c:32]([CH:36]3[CH2:37][CH2:38][NH:39][CH2:40][CH2:41]3)[cH:33][nH:34][c:35]12

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 887MethanolHCID 596006551,1-dimethylethyl 4-[7-(aminocarbonyl)-5-(3-thienyl)-1H-indol-3-yl]-1-piperidinecarboxylateHCID 596006613-(4-piperidinyl)-5-(2-thienyl)-1H-indole-7-carboxamide

Product 1

HCID 596006643-(4-piperidinyl)-5-(3-thienyl)-1H-indole-7-carboxamide

Sources & evidence

ORD record
ord-9dccb4246fa041629ea088e36a82a697
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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