(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acid → [2-(4-Trifluoromethyl-phenyl)-ethyl]-(6-trifluoromethyl-pyridin-3-yl)-amine
Reaction equation
[F:15][C:16]([c:17]1[cH:18][cH:19][c:20]([NH2:23])[cH:21][n:22]1)([F:24])[F:25].[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([CH2:9][C:10]([OH:11])=[O:12])[cH:7][cH:8]1)([F:13])[F:14]>>[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([CH2:9][CH2:10][NH:23][c:20]2[cH:19][cH:18][c:17]([C:16]([F:15])([F:24])[F:25])[n:22][cH:21]2)[cH:7][cH:8]1)([F:13])[F:14]Participants
3
Sources & evidence
- ORD record
- ord-8ecae610ac0c4817aed3c55f5ec513d4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
Loading…