1,4-Dioxane → Hydrochloric Acid

HRID 1144536Notes

Reaction equation

HRID 1144536 reaction equation
[CH3:1][N:2]([CH:3]1[CH2:4][CH:5]=[C:6]([c:9]2[c:10]([F:16])[c:11]([NH2:15])[cH:12][cH:13][cH:14]2)[CH2:7][CH2:8]1)[CH3:17].[F:18][c:19]1[cH:20][cH:21][c:22]([C:23](=[O:24])[Cl:25])[cH:26][cH:27]1.[O:28]1[CH2:29][CH2:30][O:31][CH2:32][CH2:33]1>>[CH3:1][N:2]([CH:3]1[CH2:4][CH:5]=[C:6]([c:9]2[c:10]([F:16])[c:11]([NH:15][C:23]([c:22]3[cH:21][cH:20][c:19]([F:18])[cH:27][cH:26]3)=[O:24])[cH:12][cH:13][cH:14]2)[CH2:7][CH2:8]1)[CH3:17].[ClH:25]

Participants

5

Reactant 3

HCID 312751,4-DioxaneHCID 678794-Fluorobenzoyl chlorideHCID 588523563-(4-Dimethylamino-cyclohex-1-enyl)-2-fluoro-phenylamine

Product 2

HCID 313Hydrochloric AcidHCID 58852377N-(3-(4-dimethylamino-cyclohex-1-enyl)-2-fluoro-phenyl)-4-fluoro-benzamide

Sources & evidence

ORD record
ord-4187a476b04d41779d13d4731d852ad0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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