Acetonitrile → 3-[3-oxo-7-[[4-[[2-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[1,5-a]pyrazin-7-yl]methyl]phenyl]methoxy]-1H-isoindol-2-yl]piperidine-2,6-dione
Reaction equation
[Br:1][CH2:2][c:3]1[cH:4][cH:5][c:6]([CH2:7][O:8][c:9]2[c:10]3[c:14]([cH:15][cH:16][cH:17]2)[C:13](=[O:18])[N:12]([CH:19]2[C:20](=[O:26])[NH:21][C:22](=[O:25])[CH2:23][CH2:24]2)[CH2:11]3)[cH:27][cH:28]1.[CH3:42][C:43]#[N:44].[CH:45]([N:46]([CH2:47][CH3:48])[CH:49]([CH3:50])[CH3:51])([CH3:52])[CH3:53].[F:29][C:30]([c:31]1[n:32][n:33]2[c:34]([n:39]1)[CH2:35][NH:36][CH2:37][CH2:38]2)([F:40])[F:41]>>[CH2:2]([c:3]1[cH:4][cH:5][c:6]([CH2:7][O:8][c:9]2[c:10]3[c:14]([cH:15][cH:16][cH:17]2)[C:13](=[O:18])[N:12]([CH:19]2[C:20](=[O:26])[NH:21][C:22](=[O:25])[CH2:23][CH2:24]2)[CH2:11]3)[cH:27][cH:28]1)[N:36]1[CH2:35][c:34]2[n:33]([n:32][c:31]([C:30]([F:29])([F:40])[F:41])[n:39]2)[CH2:38][CH2:37]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-ce99766b2d36493e9cf14ce1c17c39ab
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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