Ethyl Acetate → 4'-{[2-butyl-5-[4-(2-{[tert-butyl(dimethyl)silyl]oxy}-1,1-dimethylethoxy)phenyl]-4-cyclopropyl-6-oxopyrimidin-1(6H)-yl]methyl}biphenyl-2-carbonitrile
Reaction equation
[Br:1][c:2]1[c:3]([CH:28]2[CH2:29][CH2:30]2)[n:4][c:5]([CH2:24][CH2:25][CH2:26][CH3:27])[n:6]([CH2:9][c:10]2[cH:11][cH:12][c:13](-[c:16]3[c:17]([C:22]#[N:23])[cH:18][cH:19][cH:20][cH:21]3)[cH:14][cH:15]2)[c:7]1=[O:8].[C:31]([CH3:32])([CH3:33])([CH3:34])[Si:35]([O:36][CH2:37][C:38]([O:39][c:40]1[cH:41][cH:42][c:43]([B:46]([OH:47])[OH:48])[cH:44][cH:45]1)([CH3:49])[CH3:50])([CH3:51])[CH3:52].[C:53](=[O:54])([O-:55])[O-:56].[CH2:59]1[O:60][CH2:61][CH2:62][O:63][CH2:64]1.[CH3:65][CH2:66][O:67][C:68](=[O:69])[CH3:70].[Cs+:57].[Cs+:58]>>[c:2]1(-[c:43]2[cH:42][cH:41][c:40]([O:39][C:38]([CH2:37][O:36][Si:35]([C:31]([CH3:32])([CH3:33])[CH3:34])([CH3:51])[CH3:52])([CH3:49])[CH3:50])[cH:45][cH:44]2)[c:3]([CH:28]2[CH2:29][CH2:30]2)[n:4][c:5]([CH2:24][CH2:25][CH2:26][CH3:27])[n:6]([CH2:9][c:10]2[cH:11][cH:12][c:13](-[c:16]3[c:17]([C:22]#[N:23])[cH:18][cH:19][cH:20][cH:21]3)[cH:14][cH:15]2)[c:7]1=[O:8]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-ff81f4ec07004d65b7a1f41049876369
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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