Dimethylformamide → 7-(2'-Dimethylaminoethenyl)carbonyl-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid ethyl ester

HRID 1145171Notes

Reaction equation

HRID 1145171 reaction equation
[C:1]([CH3:2])(=[O:3])[c:4]1[c:5]([F:22])[cH:6][c:7]2[c:8](=[O:21])[c:9]([C:16](=[O:17])[O:18][CH2:19][CH3:20])[cH:10][n:11]([CH2:14][CH3:15])[c:12]2[cH:13]1.[C:23]([O:24][CH:28]([O:25][C:26]([CH3:27])([CH3:32])[CH3:33])[N:29]([CH3:30])[CH3:31])([CH3:34])([CH3:35])[CH3:36].[CH3:37][N:38]([CH3:39])[CH:40]=[O:41]>>[C:1]([CH:2]=[CH:28][N:29]([CH3:30])[CH3:31])(=[O:3])[c:4]1[c:5]([F:22])[cH:6][c:7]2[c:8](=[O:21])[c:9]([C:16](=[O:17])[O:18][CH2:19][CH3:20])[cH:10][n:11]([CH2:14][CH3:15])[c:12]2[cH:13]1

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 5477121,1-bis(1,1-dimethylethoxy)-N,N,N-trimethylamineHCID 13772817Ethyl 7-acetyl-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylate

Product 1

HCID 540574497-(2'-Dimethylaminoethenyl)carbonyl-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid ethyl ester

Sources & evidence

ORD record
ord-de5a901ef36e4a36a825a064f4bce54d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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