Benzene → 3-fluoro-7-chloro-5-(2-chlorophenyl)-1,3-dihydro-1-methyl-2H-1,4-benzodiazepin-2-one
Reaction equation
[CH3:22][I:23].[CH3:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30].[F:1][CH:2]1[C:3](=[O:21])[NH:4][c:5]2[c:6]([cH:16][c:17]([Cl:20])[cH:18][cH:19]2)[C:7]([c:9]2[c:10]([Cl:15])[cH:11][cH:12][cH:13][cH:14]2)=[N:8]1.[O:31]1[CH2:32][CH2:33][CH2:34][CH2:35]1.[OH2:24].[cH:36]1[cH:37][cH:38][cH:39][cH:40][cH:41]1>>[F:1][CH:2]1[C:3](=[O:21])[N:4]([CH3:25])[c:5]2[c:6]([cH:16][c:17]([Cl:20])[cH:18][cH:19]2)[C:7]([c:9]2[c:10]([Cl:15])[cH:11][cH:12][cH:13][cH:14]2)=[N:8]1Participants
7
Sources & evidence
- ORD record
- ord-792064cefd8c40a5a81ab0e7501ca252
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
Loading…