Dichloromethane → methanesulfonic acid 2-{2-[4-(4,5-Dichloro-2-fluoro-phenylamino)-6-nitro-quinazolin-7-yloxy]-ethoxy}-ethyl ester
Reaction equation
[CH3:31][CH2:32][N:33]([CH2:34][CH3:35])[CH2:36][CH3:37].[CH3:38][S:39]([Cl:40])(=[O:41])=[O:42].[Cl:1][c:2]1[cH:3][c:4]([F:30])[c:5]([NH:9][c:10]2[n:11][cH:12][n:13][c:14]3[cH:15][c:16]([O:23][CH2:24][CH2:25][O:26][CH2:27][CH2:28][OH:29])[c:17]([N+:20](=[O:21])[O-:22])[cH:18][c:19]23)[cH:6][c:7]1[Cl:8].[Cl:43][CH2:44][Cl:45]>>[Cl:1][c:2]1[cH:3][c:4]([F:30])[c:5]([NH:9][c:10]2[n:11][cH:12][n:13][c:14]3[cH:15][c:16]([O:23][CH2:24][CH2:25][O:26][CH2:27][CH2:28][O:29][S:39]([CH3:38])(=[O:41])=[O:42])[c:17]([N+:20](=[O:21])[O-:22])[cH:18][c:19]23)[cH:6][c:7]1[Cl:8]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-9a4be73d8cde406faf493b56314ac0d2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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