Ethyl Acetate → Tert-butyl 4-(6-((5-bromo-1-methyl-2-oxo-1,2-dihydropyridin-3-yl)amino)pyridin-3-yl)piperazine-1-carboxylate
Reaction equation
[Br:21][c:22]1[c:23](=[O:30])[n:24]([CH3:29])[cH:25][c:26]([Br:28])[cH:27]1.[C:31](=[O:32])([O-:33])[O-:34].[CH3:99][CH2:100][O:101][C:102](=[O:103])[CH3:104].[Cs+:35].[Cs+:36].[NH2:1][c:2]1[cH:3][cH:4][c:5]([N:8]2[CH2:9][CH2:10][N:11]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:12][CH2:13]2)[cH:6][n:7]1.[O:37]1[CH2:38][CH2:39][O:40][CH2:41][CH2:42]1.[O:45]=[C:46]([CH:47]=[CH:48][c:49]1[cH:50][cH:51][cH:52][cH:53][cH:54]1)[CH:55]=[CH:56][c:57]1[cH:58][cH:59][cH:60][cH:61][cH:62]1.[O:63]=[C:64]([CH:65]=[CH:66][c:67]1[cH:68][cH:69][cH:70][cH:71][cH:72]1)[CH:73]=[CH:74][c:75]1[cH:76][cH:77][cH:78][cH:79][cH:80]1.[O:81]=[C:82]([CH:83]=[CH:84][c:85]1[cH:86][cH:87][cH:88][cH:89][cH:90]1)[CH:91]=[CH:92][c:93]1[cH:94][cH:95][cH:96][cH:97][cH:98]1.[Pd:43].[Pd:44]>>[NH:1]([c:2]1[cH:3][cH:4][c:5]([N:8]2[CH2:9][CH2:10][N:11]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:12][CH2:13]2)[cH:6][n:7]1)[c:22]1[c:23](=[O:30])[n:24]([CH3:29])[cH:25][c:26]([Br:28])[cH:27]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-e9a640c9df584da391ed6033280f5f7f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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