Methanol → 4-((3,5-Bis(trifluoromethyl)benzyloxy)methyl)-1-(cyclopropylmethyl)-4-phenylazepane
Reaction equation
[C:36]([BH3-:37])#[N:38].[CH3:47][OH:48].[CH:31]1([CH:34]=[O:35])[CH2:32][CH2:33]1.[F:1][C:2]([c:3]1[cH:4][c:5]([CH2:6][O:7][CH2:8][C:9]2([c:16]3[cH:17][cH:18][cH:19][cH:20][cH:21]3)[CH2:10][CH2:11][NH:12][CH2:13][CH2:14][CH2:15]2)[cH:22][c:23]([C:25]([F:26])([F:27])[F:28])[cH:24]1)([F:29])[F:30].[Na+:39].[OH:40][C:41]([C:42]([F:43])([F:44])[F:45])=[O:46]>>[F:1][C:2]([c:3]1[cH:4][c:5]([CH2:6][O:7][CH2:8][C:9]2([c:16]3[cH:17][cH:18][cH:19][cH:20][cH:21]3)[CH2:10][CH2:11][N:12]([CH2:34][CH:31]3[CH2:32][CH2:33]3)[CH2:13][CH2:14][CH2:15]2)[cH:22][c:23]([C:25]([F:26])([F:27])[F:28])[cH:24]1)([F:29])[F:30]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-bf4e6b73fc1e44a08eeb05a8c99a37e1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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