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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 114574Generated: October 30, 2026

Hydrogen Bromide → 1-(3-(Bromomethyl)-4-methoxy-5-methylphenyl)-4-fluoro-1-(3-(pyrimidin-5-yl)phenyl)-1H-isoindol-3-amine

https://huagongshe.com/reaction/114574

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrogen BromideHCID 260—
ReactantSodium ionHCID 923—
ReactantDichloromethaneHCID 6344—
ReactantCarbonate IonHCID 19660—
Reactant(5-(3-Amino-4-fluoro-1-(3-(pyrimidin-5-yl)phenyl)-1H-isoindol-1-yl)-2-methoxy-3-methylphenyl)methanolHCID 58579497—
Product1-(3-(Bromomethyl)-4-methoxy-5-methylphenyl)-4-fluoro-1-(3-(pyrimidin-5-yl)phenyl)-1H-isoindol-3-amineHCID 58579476—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-364e4e20f7ca4f42ba593110d7a6b842
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)