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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1145780Generated: November 2, 2026

Sodium ion → 8-Benzyl-2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-(4-fluorophenyl)-8-azabicyclo[3.2.1]octane

https://huagongshe.com/reaction/1145780

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium ionHCID 923—
ReactantWaterHCID 962—
Reactant2-MethylpentaneHCID 7892—
ReactantTetrahydrofuranHCID 8028—
Reactant3,5-Bis(trifluoromethyl)benzyl bromideHCID 122573—
ReactantHydrideHCID 166653—
Reactant8-Benzyl-1-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-2-olHCID 69684694—
Product8-Benzyl-2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-(4-fluorophenyl)-8-azabicyclo[3.2.1]octaneHCID 88039271—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-da50ada01fa54afd94f8103d060c3c46
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)