Sodium ion → 8-Benzyl-2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-(4-fluorophenyl)-8-azabicyclo[3.2.1]octane
Reaction equation
[CH2:3]1[O:4][CH2:5][CH2:6][CH2:7]1.[CH2:8]([c:9]1[cH:10][cH:11][cH:12][cH:13][cH:14]1)[N:15]1[C:16]2([c:24]3[cH:25][cH:26][c:27]([F:30])[cH:28][cH:29]3)[CH:17]([OH:23])[CH2:18][CH2:19][CH:20]1[CH2:21][CH2:22]2.[CH3:47][CH2:48][CH2:49][CH:50]([CH3:51])[CH3:52].[F:31][C:32]([c:33]1[cH:34][c:35]([CH2:36][Br:37])[cH:38][c:39]([C:41]([F:42])([F:43])[F:44])[cH:40]1)([F:45])[F:46].[H-:1].[Na+:2].[OH2:53]>>[CH2:8]([c:9]1[cH:10][cH:11][cH:12][cH:13][cH:14]1)[N:15]1[C:16]2([c:24]3[cH:25][cH:26][c:27]([F:30])[cH:28][cH:29]3)[CH:17]([O:23][CH2:36][c:35]3[cH:34][c:33]([C:32]([F:31])([F:45])[F:46])[cH:40][c:39]([C:41]([F:42])([F:43])[F:44])[cH:38]3)[CH2:18][CH2:19][CH:20]1[CH2:21][CH2:22]2Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-da50ada01fa54afd94f8103d060c3c46
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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