Dichloromethane → 1-(1H-indazol-5-yl)-3-(4-methylpyridin-3-yl)imidazolidin-2-one

HRID 1145855Notes

Reaction equation

HRID 1145855 reaction equation
[CH3:8][c:9]1[c:10]([N:15]2[C:16](=[O:37])[N:17]([c:20]3[cH:21][c:22]4[cH:23][n:24][n:25]([CH2:29][O:30][CH2:31][CH2:32][Si:33]([CH3:34])([CH3:35])[CH3:36])[c:26]4[cH:27][cH:28]3)[CH2:18][CH2:19]2)[cH:11][n:12][cH:13][cH:14]1.[Cl:38][CH2:39][Cl:40].[F:1][C:2]([F:3])([F:4])[C:5]([OH:6])=[O:7]>>[CH3:8][c:9]1[c:10]([N:15]2[C:16](=[O:37])[N:17]([c:20]3[cH:21][c:22]4[cH:23][n:24][nH:25][c:26]4[cH:27][cH:28]3)[CH2:18][CH2:19]2)[cH:11][n:12][cH:13][cH:14]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 687857481-(4-Methyl-pyridin-3-yl)-3-[1-(2-trimethylsilanyl-ethoxymethyl)-1H-indazol-5-yl]-imidazolidin-2-one

Product 1

HCID 498719661-(1H-indazol-5-yl)-3-(4-methylpyridin-3-yl)imidazolidin-2-one

Sources & evidence

ORD record
ord-be13779fe8a9439194d462171b86130a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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