Methanol → 2-(3-{5-[5-(1-Amino-1-methyl-ethyl)-pyridin-2-ylamino]-1-methyl-6-oxo-1,6-dihydro-pyridin-3-yl}-2-hydroxymethyl-phenyl)-6-tert butyl-8-fluoro-2H-phthalazin-1-one
Reaction equation
[CH3:50][OH:51].[Li+:49].[NH2:1][C:2]([CH3:3])([CH3:4])[c:5]1[cH:6][cH:7][c:8]([NH:11][c:12]2[cH:13][c:14](-[c:20]3[c:21]([CH2:22][O:23][C:24](=[O:25])[CH3:26])[c:27](-[n:31]4[c:32](=[O:46])[c:33]5[c:34]([F:45])[cH:35][c:36]([C:41]([CH3:42])([CH3:43])[CH3:44])[cH:37][c:38]5[cH:39][n:40]4)[cH:28][cH:29][cH:30]3)[cH:15][n:16]([CH3:19])[c:17]2=[O:18])[n:9][cH:10]1.[O:52]1[CH2:53][CH2:54][O:55][CH2:56][CH2:57]1.[OH-:48].[OH2:47]>>[NH2:1][C:2]([CH3:3])([CH3:4])[c:5]1[cH:6][cH:7][c:8]([NH:11][c:12]2[cH:13][c:14](-[c:20]3[c:21]([CH2:22][OH:23])[c:27](-[n:31]4[c:32](=[O:46])[c:33]5[c:34]([F:45])[cH:35][c:36]([C:41]([CH3:42])([CH3:43])[CH3:44])[cH:37][c:38]5[cH:39][n:40]4)[cH:28][cH:29][cH:30]3)[cH:15][n:16]([CH3:19])[c:17]2=[O:18])[n:9][cH:10]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-00cafaffca934df88d0e105f5a2b681e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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